I did a research paper this summer on this subreddit and there was a published study that found that 74% of attacks on Reddit came from 1% of source subreddits. I assume that subs like r/Drama are the 1%.
Meth actually predates the invention of amphetamine by a bit. It was largely interchangeable at first I think, with amphetamine just being more common. Illicit meth though only really exploded in the 80s because of laws that clamped down on certain precursors to amphetamine, which made producing meth easier than producing pure amphetamine. Actually the easiest way to produce amphetamine is to produce meth and then make amphetamine from that.
Interesting, thank you watermark. I know meth is just like a racemic mix that is pretty simple to synthesize. And yeah an oral form would be somewhat interchangeable, hard to think anything but “freebase” when you think meth.
Amphetamine and methamphetamine are both racemic mixes whenever they're synthesized usually. Pharmaceutical preparations usually have another step to filter out the levo- melocules because those are not as psychologically active and largely just get in the way (an interesting exception is adderall, where it's half racemic half pure dex, so 75% dex). Illicit preparations almost never bother to do this though, they usually don't have much chemical knowledge to begin.
Freebasing is another step... not 100% sure what the process behind this is actually. It doesn't actual change the chemical that gets into the blood of course.
Yep yep, that makes sense. The adderall is a confusing one. Personal experience is that it’s less harsh on the cardiovascular system, but that’s probably just dependent on metabolizing enzyme distribution. Wonder if the left hand has some weird kinetics on the dex that wouldn’t be apparent in illicit racemic preparations?
Someone on here was telling me they were on transdermal methylphenidate, not a shocking development but still surprised they tried all of the pro-drug abuse deterrent before going with that. Everyone I’ve spoken to feels the Lisdexamfetamine route really didn’t work for extended release as claimed.
Levoamphetamine is more noted for a "body load", physical effects. It causes you to be more nervous, for your heart rate to shoot up, little to no actual euphoria though. Dextroamphetamine is the main thing responsible for the euphoria and mental alertness. Adderall should indeed be less harsh on the cardiovascular system than racemic street speed, but not as light as vyvanze or pure dextroamphetamine. Unfortunately rarely prescribed, due to marketing from Shire which wants everyone to use adderall even though it's really no better. It's kind of seen as some weird shady shit from the 70's by doctors that people want to get to abuse and dance all night with, whereas Adderall is this new and fancy serious ADD medicine. Which is retarded, but whatever.
Transdermal ritalin, I feel they're trying to make up for ritalin's extraordinarily short half life with some kind of fancy extended release stuff. Vyvanse (lisdexamfetamine) is supposedly extended release, but they mechanism really is not *that* extended release IMO. I have a bit of trouble tell the difference really. It's like amphetamine with maybe an extra hour of effect overall and an hour gentle onset period. But it should hardly be used as an all day thing like they try to do. Honestly if they'd just drop that, split it into two, and make it twice daily it might work a lot better. Rather than pretending that it's an Adderall XR killer.
Pretty on the mark, you know your stimulants. Especially the “weird shit” with Vyvanse, I never worked to isolate any variables but I’m guessing diet or something, or the metabolizing by the liver if it was busy. Totally different drug at the same dose too often. Lisdex marketing was “9-12 hours blah blah blah”, usually lasted about 7.5ish if I’m generous and that’s at 70 mg.
You should read up on Mydayis. Shiny new super-super Adderall XR to milk a patent. I switched off of it to medium dose Adderall XR due to insurance and there is 0 difference in duration. I don’t think it will sell well, but I think they are just shuffling patents at this point.
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Its neurotoxic effects, however, were not known until much later, with the first paper definitively identifying MPP+ as a Parkinson's-inducing poison being published in 1983.
Also lol at this:
This paper followed a string of poisonings that took place in San Jose, California in 1982
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And meth coincidentally raises your dopamine levels, which treats this disease that only appears when you have too little dopamine. Meaning part of why he was taking meth was likely his Parkinson's disease.
...If this was far enough in the past that we had no biological understanding of the disease or available medical treatments for that condition just like having Parkinsons in 1945, sure. If not, then no.
Eventually you get adjusted to pretty much any non lethal dosage of amphetamine. The thing about amphetamine is that since it is a dopamine releaser, it has a pretty definite ceiling of effect after which more doesn't do much good. Cus you've already dumped all the dopamine in your system.
I have no idea man, try l-dopa or tyrosine to see if you feel any better. L-dopa is the medication for parkinsons which is in the plant mucuna purens and gets converted to dopamine, and tyrosine gets converted into l-dopa then dopamine by the bh4 enzyme, maybe if you feel better then that suggests something. But I'm not a doctor
That won't necessarily produce a high or anything... The thing is that even if you add to dopamine reserves, it doesn't necessarily get released. The reason l dopa works for Parkinsons is that the production centers shut down, so the l dopa replaces that source of dopamine.
Maybe together it would help combat amphetamine tolerance but tbh I doubt it.
Barely able to contain the excitement as he gets ready to let the world know how offended he is, and climax at the very moment he presses the ban button for comments that make him feel bad.
How is this the first time I've seen this? It's fucking hilarious. The subtitle is interesting too, the nazies actually did utilize meth for productivity reasons, especially the luftwaffal so their pilots could go bombing 24/7. It fucked em up after a few days though, so I guess it was more like 24/3. And then they'd have to go to sleep for 20 hours.
Göring was a junkie as well, but more of an opiates guy.
Apparently Hitlers doctor had him on a bizarre cocktail of medicine, stuff that would get him sanctioned by the profession today. Weird mix of quackery, alternative medicine, strong drugs, and drugs to try and counteract the side effects of all the above.
Easy to imagine it turned him from a hateful evil man into a monumentally incompetent hateful evil man. So once he was competent enough to get into power and later utterly destroyed Germany with his choices. Some of the tragedies may have been avoided.
That's quite fascinating. I haven't heard many of these drug theories until recently, if they can be well substantiated then they might go a long way in explaining the all the utter absurdities of the Third Reich.
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100 comments
1 SnapshillBot 2019-03-27
I did a research paper this summer on this subreddit and there was a published study that found that 74% of attacks on Reddit came from 1% of source subreddits. I assume that subs like r/Drama are the 1%.
Snapshots:
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1 TaysSecondGussy 2019-03-27
Is he stimming? 🔩🧮🚞👋🏻👋🏻
Hitler was a sperg confirmed.
1 TheLiveGhost 2019-03-27
Someone give him a fidget spinner god damnit
1 TaysSecondGussy 2019-03-27
Would have changed the world as we know it. Whoever thought Nationalism and domination could be a tism fixation?
1 l-Removed-l 2019-03-27
I’m pretty sure the swastika is supposed to be a four pronged fidget spinner.
1 DeathBahamutXXX 2019-03-27
Could just be all the meth the nazis did
1 TaysSecondGussy 2019-03-27
I don’t think it existed, but I could see amphetamines for sure.
1 DeathBahamutXXX 2019-03-27
History channel had a doc about it. They actually used meth and opioids.
1 TaysSecondGussy 2019-03-27
Wow, their chemists were ahead of their time. Our whitoids didn’t start making meth until decades later.
1 TehAlpacalypse 2019-03-27
coincidentally, it's still only consumed by wh*te supremacists
1 POST_BUSSY 2019-03-27
He also did a lot of cocaine via eyedrops.
https://www.historyextra.com/period/second-world-war/when-hitler-took-cocaine/
1 acidoverbasic 2019-03-27
I'm trying to imagine what numb eyeballs feel like and I don't like it.
1 POST_BUSSY 2019-03-27
What it feels like, is a good time 😎
1 POST_BUSSY 2019-03-27
To invade Russia
1 watermark08 2019-03-27
Meth actually predates the invention of amphetamine by a bit. It was largely interchangeable at first I think, with amphetamine just being more common. Illicit meth though only really exploded in the 80s because of laws that clamped down on certain precursors to amphetamine, which made producing meth easier than producing pure amphetamine. Actually the easiest way to produce amphetamine is to produce meth and then make amphetamine from that.
1 TaysSecondGussy 2019-03-27
Interesting, thank you watermark. I know meth is just like a racemic mix that is pretty simple to synthesize. And yeah an oral form would be somewhat interchangeable, hard to think anything but “freebase” when you think meth.
1 watermark08 2019-03-27
Amphetamine and methamphetamine are both racemic mixes whenever they're synthesized usually. Pharmaceutical preparations usually have another step to filter out the levo- melocules because those are not as psychologically active and largely just get in the way (an interesting exception is adderall, where it's half racemic half pure dex, so 75% dex). Illicit preparations almost never bother to do this though, they usually don't have much chemical knowledge to begin.
Freebasing is another step... not 100% sure what the process behind this is actually. It doesn't actual change the chemical that gets into the blood of course.
1 TaysSecondGussy 2019-03-27
Yep yep, that makes sense. The adderall is a confusing one. Personal experience is that it’s less harsh on the cardiovascular system, but that’s probably just dependent on metabolizing enzyme distribution. Wonder if the left hand has some weird kinetics on the dex that wouldn’t be apparent in illicit racemic preparations?
Someone on here was telling me they were on transdermal methylphenidate, not a shocking development but still surprised they tried all of the pro-drug abuse deterrent before going with that. Everyone I’ve spoken to feels the Lisdexamfetamine route really didn’t work for extended release as claimed.
1 watermark08 2019-03-27
Levoamphetamine is more noted for a "body load", physical effects. It causes you to be more nervous, for your heart rate to shoot up, little to no actual euphoria though. Dextroamphetamine is the main thing responsible for the euphoria and mental alertness. Adderall should indeed be less harsh on the cardiovascular system than racemic street speed, but not as light as vyvanze or pure dextroamphetamine. Unfortunately rarely prescribed, due to marketing from Shire which wants everyone to use adderall even though it's really no better. It's kind of seen as some weird shady shit from the 70's by doctors that people want to get to abuse and dance all night with, whereas Adderall is this new and fancy serious ADD medicine. Which is retarded, but whatever.
Transdermal ritalin, I feel they're trying to make up for ritalin's extraordinarily short half life with some kind of fancy extended release stuff. Vyvanse (lisdexamfetamine) is supposedly extended release, but they mechanism really is not *that* extended release IMO. I have a bit of trouble tell the difference really. It's like amphetamine with maybe an extra hour of effect overall and an hour gentle onset period. But it should hardly be used as an all day thing like they try to do. Honestly if they'd just drop that, split it into two, and make it twice daily it might work a lot better. Rather than pretending that it's an Adderall XR killer.
1 LongPostBot 2019-03-27
Good job bobby, here's a star
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1 TaysSecondGussy 2019-03-27
Pretty on the mark, you know your stimulants. Especially the “weird shit” with Vyvanse, I never worked to isolate any variables but I’m guessing diet or something, or the metabolizing by the liver if it was busy. Totally different drug at the same dose too often. Lisdex marketing was “9-12 hours blah blah blah”, usually lasted about 7.5ish if I’m generous and that’s at 70 mg.
You should read up on Mydayis. Shiny new super-super Adderall XR to milk a patent. I switched off of it to medium dose Adderall XR due to insurance and there is 0 difference in duration. I don’t think it will sell well, but I think they are just shuffling patents at this point.
1 trappysaruh 2019-03-27
wow never seen this about hitler before
1 [deleted] 2019-03-27
[removed]
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1 trappysaruh 2019-03-27
i see ur comment
1 WarSanchez 2019-03-27
😘 wanna see something else?
1 trappysaruh 2019-03-27
wut
1 WarSanchez 2019-03-27
Chicken Butt
1 trappysaruh 2019-03-27
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
1 LongPostBot 2019-03-27
still unemployed then?
I am a bot. Contact for questions
1 [deleted] 2019-03-27
[removed]
1 AutoModerator 2019-03-27
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1 high_side 2019-03-27
The best part of this bot is that I can fill in the gaps knowing just one word from the comment.
1 TaysSecondGussy 2019-03-27
That and the fact that it dabbed the living shit out of you-know-who. Pretty based.
1 trappysaruh 2019-03-27
😄
1 Ed__ButteredToast 2019-03-27
Hot
1 Doctor-Pavel 2019-03-27
whose benis was more masculine: yours or Hitler's?
1 trappysaruh 2019-03-27
g-slur
1 Doctor-Pavel 2019-03-27
did you mean "h-slur"?
1 Crankyoldhobo 2019-03-27
lmao b-slur, you f-slur f-slur.
1 nicerredditaccount 2019-03-27
Having one ball is alpha because having 2 of something is like boobs and having 1 of something is like a penis.
1 CrackIsHealthy4U 2019-03-27
Hitler had Parkinsons most likely. As a member of the master race, his brain was shutting down the production of chemicals he needs to live.
1 demotecontrol 2019-03-27
Is there a way to learn this power, only do it instantly?
1 CrackIsHealthy4U 2019-03-27
https://en.wikipedia.org/wiki/MPP%2B
1 demotecontrol 2019-03-27
Holy shit there is.
1 TehAlpacalypse 2019-03-27
I'm ootl on this one, explain?
1 SpiceAndEvNice 2019-03-27
Also lol at this:
1 TaysSecondGussy 2019-03-27
Classic story. Chemistry grad student trying to do hard Pharmacology smdh tbh.
1 [deleted] 2019-03-27
[removed]
1 AutoModerator 2019-03-27
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1 ottawabrandonwright 2019-03-27
Hitler did a shit ton of meth dude
1 CrackIsHealthy4U 2019-03-27
And meth coincidentally raises your dopamine levels, which treats this disease that only appears when you have too little dopamine. Meaning part of why he was taking meth was likely his Parkinson's disease.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC491901/
As it turns out, you don't become immunized from Parkinsons by taking Meth beforehand.
1 UrMumsMyPassword 2019-03-27
Sounds like a problem that can only be solved with even more meth
1 JustLions 2019-03-27
That's your answer for everything.
1 UrMumsMyPassword 2019-03-27
Not true. As a mayo I also have to endorse fentanyl.
1 Baking-Soda 2019-03-27
Poppin xanniees
1 DoctorMort 2019-03-27
Using the amount of amphetamines he used to treat Parkinson's is like using a shotgun to get rid of a sliver in your finger.
1 CrackIsHealthy4U 2019-03-27
...If this was far enough in the past that we had no biological understanding of the disease or available medical treatments for that condition just like having Parkinsons in 1945, sure. If not, then no.
1 DoctorMort 2019-03-27
thanks /u/CrackIsHealthy4U
1 watermark08 2019-03-27
Eventually you get adjusted to pretty much any non lethal dosage of amphetamine. The thing about amphetamine is that since it is a dopamine releaser, it has a pretty definite ceiling of effect after which more doesn't do much good. Cus you've already dumped all the dopamine in your system.
1 lenovolegion 2019-03-27
Stimming occurs due to high dopamine. If parkinson is a lack of dopamine why does he stim here?
1 CrackIsHealthy4U 2019-03-27
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4683874/
1 lenovolegion 2019-03-27
Alright but if i stim (not as much as this) does it mean i have parkinsons or high dopamine?
1 CrackIsHealthy4U 2019-03-27
Pretty sure anyone can stim
1 lenovolegion 2019-03-27
I meant my baseline is that
1 CrackIsHealthy4U 2019-03-27
I have no idea man, try l-dopa or tyrosine to see if you feel any better. L-dopa is the medication for parkinsons which is in the plant mucuna purens and gets converted to dopamine, and tyrosine gets converted into l-dopa then dopamine by the bh4 enzyme, maybe if you feel better then that suggests something. But I'm not a doctor
1 watermark08 2019-03-27
That won't necessarily produce a high or anything... The thing is that even if you add to dopamine reserves, it doesn't necessarily get released. The reason l dopa works for Parkinsons is that the production centers shut down, so the l dopa replaces that source of dopamine.
Maybe together it would help combat amphetamine tolerance but tbh I doubt it.
1 TreLoon 2019-03-27
Are we sure he wasn't the original fent addict? 🤔
1 KingNothing305 2019-03-27
The master race really likes meth
1 korri123 2019-03-27
That's actually disputed.
1 TheMayorOfHounslow 2019-03-27
That's total b.s. plus did meth even exist back then?
1 ottawabrandonwright 2019-03-27
Youre retarded. And yes.
1 TheMayorOfHounslow 2019-03-27
Aka a dramatard
1 POST_BUSSY 2019-03-27
That's not a nice thing to call SRD mods
1 BasicallyADoctor 2019-03-27
This video is speed up about 2x. Still looks like a sperg but not as much
1 mohkohnsepicgun 2019-03-27
Man loved him some athletics... up 'till the point where Jessie Owens won.
1 niggerpenis 2019-03-27
He looks like he can't wait to go home to play with his model trains
1 POST_BUSSY 2019-03-27
I wonder if he has miniature Jews to go along with his model train set.
1 charming_tatum 2019-03-27
Did they have easy bake oven back then?
1 CrackIsHealthy4U 2019-03-27
Barely able to contain the excitement as he gets ready to let the world know how offended he is, and climax at the very moment he presses the ban button for comments that make him feel bad.
1 high_side 2019-03-27
I only see dramanats in that gif.
1 POST_BUSSY 2019-03-27
Why did you guys doxx Phedre?
1 DannedFromBrama 2019-03-27
me when a nice ass walks in and i cant go sniff
1 BlessThisBussy 2019-03-27
Just mething around
1 hallowed-rick 2019-03-27
Does he need to pee?
1 EarlCampbellsMeat 2019-03-27
this is me at some lame event geeked up but i just wanna go home and beat my shit for hours
1 Ed__ButteredToast 2019-03-27
What a sperg lmao
1 dc_snuff_film 2019-03-27
this cute boy can bounce his meth bussy on my dick any day
1 watermark08 2019-03-27
Jesus Christ is he downs or something
1 ztoundas 2019-03-27
Meth did the holocaust
1 SJCards 2019-03-27
I'm still serving my latest 69 day ban 😢
1 SJCards 2019-03-27
/u/snallygaster unbanz kthx
1 Monkits 2019-03-27
How is this the first time I've seen this? It's fucking hilarious. The subtitle is interesting too, the nazies actually did utilize meth for productivity reasons, especially the luftwaffal so their pilots could go bombing 24/7. It fucked em up after a few days though, so I guess it was more like 24/3. And then they'd have to go to sleep for 20 hours.
Göring was a junkie as well, but more of an opiates guy.
1 SandorClegane_AMA 2019-03-27
Apparently Hitlers doctor had him on a bizarre cocktail of medicine, stuff that would get him sanctioned by the profession today. Weird mix of quackery, alternative medicine, strong drugs, and drugs to try and counteract the side effects of all the above.
Easy to imagine it turned him from a hateful evil man into a monumentally incompetent hateful evil man. So once he was competent enough to get into power and later utterly destroyed Germany with his choices. Some of the tragedies may have been avoided.
1 Monkits 2019-03-27
That's quite fascinating. I haven't heard many of these drug theories until recently, if they can be well substantiated then they might go a long way in explaining the all the utter absurdities of the Third Reich.
1 ihaztacos 2019-03-27
Ze fuhrer just taking fat rips off that 100/0 cut meth
OOF !
1 katthecat666 2019-03-27
seriouspost warning, Blitzed is a genuinely good read, would highly recommend
1 TheMayorOfHounslow 2019-03-27
This n-word tweakin 😂😂🤣🤣🤣😅😲😲😬😬😬
1 Caqo 2019-03-27
Holy shit hitler has autism
1 AutoModerator 2019-03-27
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