50mg of dph in every 3ml

so imagine u just need some real sleep (ur actually tired not a druggie) and pour a medicine cup of this shit.

if you pour 10ml of this shit ur on about 166mg of dph (dph is commonly known as benadryl. in large doses it is a deleriant hallucinogen.)

if you pour 20ml then u are on 333mg of dph (at this range u are definitely going to trip. for my weight this is a threshold dose)

if you got those 30ml cups and pour some of this shit you are definitely tripping balls u finna be seeing Satan dragging you and yo granny to heck n shit 🤣🤣 spiders n snakes coming to get yo butt fasho neighbor 😭😭

not to mention if u think "darn this shit not helping me sleep I better take some more". nah neighbor yo butt goin straight to the afterlife it's over for you

for those of yall who don't know what dph is go to /r/dph or google dph abuse that shit is wicked ur literally better off takin heroin than this shit

Source

Hello users of rdrama.net and welcome to the first edition of...

LAPPLAND'S CHEMICAL SERIES

Today I will show you the process of methamphetamine manufacture.

Please keep in mind that the manufacture of methamphetamine is illegal and so is the sale and consumption. I @Lapp have never taken produced or sold methanphetamine. I do not personally condone the manufacture sale or consumption of methamphetamine.

rdrama.net does not condone the manufacture sale or consumption of methamphetamine.

If you struggle with meth addiction please contact the American addiction center at

406-220-5357or get help on the web at https://www.samhsa.gov/find-help

If you find yourself in any way replicating the process of meth production please contact your local police department so that they can assist you and get you the help that you need.

The creation of this post was endorsed by @carpathianflorist all legal issues are solely their responsibility

I still do not know what SWIM style is please inform me in the comments.

This guide is for education and informational purposes and is not to be replicated.

what is methamphetamine ?

Meth is a strong central nervous system stimulant that was discovered in 1893. Methamphetamine properly refers to the equal mix of levomethamphetamine and dextromethamphetamine in their pure amine forms though the most commonly known version of methamphetamine is the hydrochloride salt version commonly known as crystal meth. Methamphetamine was once readily available as an over the counter medication, the earliest prescriptions for it were for treating hay fever, asthma, and the common cold. During the second world war meth was given to soldiers to improve their performance. Factory workers and other laborers were also given methamphetamine to keep them awake and capable of working longer, it is during this time that the negative side effects of meth use started to be discovered. The first meth ban in the United States occurred in 1959 when meth based inhalers were regulated to stop abuse with them. Later in the 1970's and 1980's stricter restrictions pushed methamphetamine into being a schedule II substance. Despite its illegality meth manufacture has continued until today and due to many restrictions placed upon the process and materials meth manufacturing is a hard and dangerous process.

equipment

The manufacturing of meth requires at minimum the following materials:

Several round bottom flasks, a claisen adapter for the round bottom flasks, a still head that has a thermometer holder, Two condensers with straight central tubes one 35 cm long and the other 50 cm long, a vacuum adapter,a separator funnel, and multiple 24/40 size ground glass joints.You will need at least one each of the following round bottom flask: 3000 ml, 2000 ml and 500 ml; and two each of 1000 mi and 250 ml. I am not sure if changing the equipment type for a suitable replacement is possible or if the exact specifics really matter, I have never undergone these processes as they are illegal.

Due to the abuse of drug manufacturing most chemistry supply companies keep extensive records of customers and require an account to be set up before hand to purchase.

chemicals

The following are the necessary precursor chemicals:

Listed Precursor Chemicals:

1. Anthranilic acid and anthranilic acid salt

2. Benzyl cyanide

3. Ergonovine and ergonovine salt

4. Ergotamine and ergotamine salt

5. N-Ergotamine acid and N-Ergotamine salt

6. Norpseudoephedrine, norpseudoephedrine salt, norpseudoephedrine optical isomers, and norpseudoephedrine salts of optical isomers

7. Phenylacetic acid, phenylacetic esters (such as ethylphenylacetate) and phenylacetic salts

8. Phenylpropanolamine, phenylpropanolaminesalts, phenylpropanolamine optical isomers, and phenylpropanolamine salts of optical isomers

9. Piperidine and piperidine salts

10. Pseudoephedrine, pseudoephedrine salts, pseudoephedrine optical isomers, and Pseudoephedrine salts of optical isomers

11. 3, 4-Methylenedioxyphenyl-2-propanone

12. Methylamine and methylamine salts

13. Ethylamine and ethylamine salts

14. D-lysergic acid, its salts, optical isomers, and salts of optical isomers

15. Propionic anhydride

16. lsosafrole

17. Safrole

18. Piperonal

19. N-Methylephedrine, its salts, optical isomers, and salts of optical isomers

20. N-Ethylephedrine, its salts, optical isomers, and salts of optical isomers

21. N-methylpseudoephedrine, its salts, optical isomers, and salts of optical isomers

22. N-ethylpseudoephedrine, its salts, optical isomers, and salts of optical isomers

23. 57% Hydriotic acid

24. Ephedrine

25. Benzaldehyde

26. Nitroethane

27. GBH

28. Red Phosphorus; white or yellow Phosphorus

29. Hypophosphoric Acid, and its salts

30. lodine (must be over 2% tinticture)

31. N-phenethyl-4-piperidone

The following are necessary essential chemicals

list of essential chemicals:

1. Acetic anhydride

2. Acetone

3. Benzyl chloride (4 kg)

4. Ethyl ether

5. Potassium permanganate

6. 2-Butanone

7. Toluene

8. Acetic anhydride

9. Benzyl chloride

10. Ethyl ether

11. Potassium permanganate

12. 2-Butatone

13. Toluene

14. lodine

15.Acetone

process

This is an example of the Leuckart-Wallach reaction. This reaction converts aldehydes or ketones to amines by reductive amination in the presence of heat. The Leuckart-Wallach can convert phenylacetone into meth. The process that will occur is shown in a diagram below:

the process of creating phenylacetone is shown in the diagram below:

the process of creating N-methylformamide is shown below:

To test the two productsi in a glass test tube there should be one part N-methylformamide for every two parts phenylacetone for the reaction, at this point simply putting them together in a test tube will cause them to mix together. The Leuckart-Wallach reaction method is highly sensitive and if not done right will create a red like tar substance instead of the desired methanphetamine, if a red tar like substance is created as a result of the N-methylformamide and phenylacetone reacting in the test tube then there was water present in the reaction and the process to create both chemicals must be restarted.

If the red tar like substance is not created then the full reaction between the N-methylformamide and phenylacetone may proceed. For the full reaction there must be one part phenylacetonefor every 2.5 parts N-methylformamide. Though apparently the amount of N-methylformamide can vary from 2 parts to 3 parts and still be perfectly fine to react. The two chemicals should be mixed together in a 500ml round bottom flask, the flask should be set in a container filled 2/3 of the way with oil on a burner to apply even heat throughout the flask as the chemicals react. The oil may be vegetable oil or a subsitute oil which can similarly evenly distribute heat through the round bottom flask as desired. A metal pan is fine container for the oil as it will allow the contents of the glass round bottom flask to be seen. As heat is applied the contents of the flask should be stirred regularly with a thermometer. The temperature of the oil bath should be brought to 100° C over the course of 45 minutes or so. Once it reaches this temperatuee, the heat is turned back down so that the chemicals may stabilize at this point. Every degree of temperature must be closely monitored from this point forward. The temperature of the contents of the flask is heated up to 105° C. The chemicals in the flask must bestirred every 15 minutes. At about 105° C, the reaction will start, although sometimes the mixture's temperature must go as high as 110° C before the reaction starts When the reaction starts, the contents of the flask begin to bubble. After the reaction starts the temperature must be lowered down to the initial heat that the mixture started to react at. It may be left at this state for several hours. Tap water flow is proper for use in the condenser. The heat should be turned on to the 500 ml flask, and a gentle rate of boiling is to be maintained for 2 hours. The mixture should turn black. The reaction going on here is methamphetamine formyl amide. his is a hydrolysis reaction. After the two hours have passed, the heat to the flask is turned off. While the flask is cooling down, 80 grams of sodium hydroxide and 250 ml of water are mixed in a 1000 ml round bottom flask. When both flasks have cooled down, the black reaction mixture is cautiously added to the sodium hydroxide solution. It is added in small portions, and then swirled around to mix it. They react together quite violently. The reaction here is sodium hydroxide reacting with hydrochloric acid to produce table salt, with formic acid to produce sodium formate, and with methamphetamine hydrochloride to produce methamphetamine free base. At this point the mixture must be distilled. The salt will form at the bottom of the flask and not react with the liquid substance within, After the mixture is distilled either toluene or ethyl can be used as the solvent to make the crystals in. With whatever solvent is used the insides of the condenser, vacuum adapter and 250 ml flask must be rinsed to get out the methamphetamine clinging to the glass. This rinse is poured in with the product. Solvent is added to each of the Erlenmeyer flasks until the volume of liquid is 300 ml. They are mixed by swirling. Then the sulfuric acid is then added to the solution and anair blower is started to slowly keep the fumes of dry HCI flowing into the meth free base rather than ever being sucked backwards.Within a minute of bubbling, white crystals begin to appear in the solution. to filter the crystals out. There should be a small amount of formic acid added as it acts as a catalyst. The formic acid should be buffered by the presence of free methylamine, to prevent the pH of the reaction mixture from falling too low and becoming acidic. The presence of water in the reaction mixture will cause the reaction to not happen. It prevents the phenylacetone from dissolving in the N-methylformamide, which creates low yields of purple-colored crystal. The filtering flask and Buchner funnel are set up now. The drain stem of the Buchner funnel must extend through the rubber stopper, because methamphetamine will dissolve rubber. A piece of filter paper must cover the flat bottom of the Buchner funnel. The vacuum is turned on and the hose attached to the vacuum nipple. Then the crystals are poured into the Buchner funnel. The solvent and the uncrystallized methamphetamine pass through the filter paper and the crystals stay in the Buchner funnel as a solid cake. About 15 ml of solvent is poured into the Erlenmeyer flask. The top of the flask must be covered and shaken to suspend the crystals left clinging to the sides. This is also poured into the Buchner funnel. Finally, another 15 ml of solvent is poured over the top of the filter cake.after this the vacuum hose is disconnected and the Buchner funnel. All of the filtered solvent is poured back into the Erlenmeyer flask it came from. It is returned to the HCI source for more bubbling. The Buchner funnel is put back into the top of the filtering flask. It still contains the filter cake of methamphetamine crystals. The vacuum shluld be turned back on, the vacuum hose must be attached to the filtering flask, and the top of the Buchner funnel is covered. The vacuum builds and removes most of the solvent from the filter cake. as the filtering process continues, one flask is being filtered while the other one is being bubbled with HCl. Solvent is added to the Erlenmeyer flask to keep their volumes at 300 ml. Eventually, after each flask has been bubbled for about seven times, no more crystal will come out and production process is finished.

the end

Thank you for reading this far, please keep in mind that this process is illegal and that replicating any of it in part or in whole should not be done. Meth is a terrible substance that should not be consumed. I do not support the production or consumption of any illicit materials and neither does rdrama.net

Join me for the next edition of LAPPLAND'S CHEMICAL SERIES where I will teach the members of !cuteandvalid how to create estrogen for the use in male to female transitioning with just a plastic bag and a bathtub.

!druggies !boozers

Time to get r-slurred!!

I JUST GOT FIRED BECAUSE OF THIS FUCKING APP! pic.twitter.com/Rq9bKXOQce

— ıʌɐſ (@javioffa30) January 5, 2024

basically this guy smokes fentanyl in burger king and streams himself getting high on kick. he claims to go to work off of 15 percs. some random guys, probably undercover feds, show up at his work to give him free pills and he decides to post about it (i think it's been deleted). he gets fired then decides to post that police are at his house

i suggest you go through his profile! he's very dramatic and people always poke and insult them and he fights them in the comments

this trip has showed me that the earth truly is flat. while tripping i could see all dimensions and side of our planet and it was 100% flat. im sure i was meant to experience this now and i truly belive i am god and i created this flat earth. all hail me or you shall vanish

I'M AWESOME PLEASE GIVE ME ATTENTION I'M IN PSYCHOSIS PLEASE VALIDATE ME

Very common thoughts among the uninitiated.

i diddnt plan it i just did for no reason

based, get this man his keys

i can proudly say i drove during this

u from baltimore homeboy, lmk where you at and if you need a fade cuz ion take shi from jits

Thought I would make a personal tier list of my favorite legal highs (at least legal in the only country that matters )

This list is NOT extensive or complete, just my personal favs and hates. This is not a list of prescription drugs, just stuff you can order on the clear web or get OTC at stores. I'm also skipping cannabis because it's not legal everywhere yet (and it's for strags )

Let's get started then, shall we?

SHIT TIER

Nicotine

I really don't need to say much about why nicotine sucks in all it's forms. It's just not worth taking.

BORING TIER

Alcohol

Alcohol is one of the weakest, shortest duration, and most overall toxic of the GABAergics that I've taken. It's also just really uninteresting and generally uncomfortable.

L-Theanine

Theanine is really only good with Caffeine. On it's own, it does next to nothing. Taking a large dose almost feels like a small dose of gabapentin.

Racetams and Noopept

Not much to say about them. Minor stimulation and a slight 'glow' at mid-high doses. People swear by their nootropic abilities, and I have noticed a moderate increase in memory recall before.

DECENT TIER

Caffeine

Caffeine, especially in energy drink form, is great for when you want to focus, but still kinda relax - like playing a game, having a conversation with friends, or doing some chores. It's pretty nice being somewhat stimulated but not feeling the need to do things constantly, like with amphetamines.

It's also pretty tasty in most forms, and can actually be quite relaxing, especially when combined with L-Theanine (like in green tea). Best used occasionally (as I know you all have extremely high caffeine tolerance and will say it does nothing for you anymore )

Salvia

Salvia is one of those drugs that's extremely interesting conceptually, but kinda sucks in practice.

Sweating and discomfort followed by becoming an inanimate object for 2000 years, followed by days of depression. It's unique and worth checking out if you're adventurous. It's also probably the strongest drug on this list.

GBL / GHB / 2M2B

Is your alcohol making too much acetaldehyde in your stomach and poisoning you the next day? Yeah, it does that.

Would you prefer that your alcohol hit much harder but last less time? GBL/GHB are a good solution. A literal cleaning solution, at that!

Are you feeling scammed that the shot of vodka you bought didn't last 14 hours? Try 2M2B!

Final thoughts: These are all very interesting GABAergics with differing use cases, but not for me.

DPH

Diphenhydramine is great if you want to see spiders, shadow men, and horrors from another dimension while also constantly forgetting where you are and what's happening. It's a genuinely interesting experience, and it causes dream-like structures to appear in your waking reality as opposed to the geometry of psychedelics, meaning it has the most 'realistic graphics' of any hallucinatory drug.

It's also good at a low dose for fapping. Not sure why.

GREAT TIER

Kratom

Kratom is a south east asian plant which contains the indole alkaloid mitragynine. It's an opioid with relaxing or stimulating effects, depending on the dose. Pretty cool. It can hit very hard the first few times (or if you combine it with 30-60mg of DXM to reset your tolerance ) and can even make you 'nod' like a traditional opioid. It does have a sort of 'built-in abuse mitigation' in that it will make you violently nauseated if you reach a certain dose (which depends on you and your tolerance).

Kratom is a great drug to relax, to prevent pain while doing physical work , or to be social. It's also amazing for essentially eliminating stimulant come-downs.

Nitrous Oxide

Nitrous is a 'turbo button' for psychedelics, dissos, cannabis, and a slew of others. On it's own, it's a bit weak, but combine it with certain drugs and you will be shot to the fricking moon. It's really no joke - but it only lasts about 30 seconds. Still, an amazing substance if you're already high - and, being a dissociative, it actually prevents anxiety during the blast-off (unlike using cannabis to enhance psychedelics).

WAWAWAWAWAWAWAWA

GOD TIER

Phenibut

Phenibut is a gabapentinoid that, interestingly, acts on GABA B (and also A). It's basically alcohol, with less mental impairment, that lasts for 12-16 hours, has high levels of euphoria, enhances music, makes every shot of alcohol 4x stronger, and makes you a gigachad socially. It's also legal, cheap (if you can find it these days), and doesn't have a hangover - in fact, you'll feel GREAT the next day because of how well you'll sleep.

The best part about phenibut's social aspect is that it makes you more empathetic, like MDMA.

There's only really one downside - it takes 6 hours to really 'kick in', so prepare ahead of time.

DXM

DXM has a reputation of being a 'teenager drug', but the people who say that haven't taken a 3rd plateau dose.

DXM is a very powerful dissociative opioid with SSRI properties. What does this mean? - It means that DXM acts like an unholy amalgamation of ketamine, codeine, and MDMA. It also happens to reset your tolerance to stimulants and opioids, and is being researched as an antidepressant. It's also by FAR the best drug for music enhancement. This is not debatable.

There are four different 'plateaus' of DXM doses, which all have unique effects. The most interesting are 2nd and 3rd plateau - 2nd plateau is excellent for music listening and fading into the background of reality. It also makes you want to move your body, as every motion feels incredible. You'll be stumbling like an r-slur though.

In contrast, if you move around a lot on 3rd plateau, you'll vomit. Hard. 3rd plateau will suck you deep into a dark, boundless expanse of dream-like structures and voids. It's impossible to explain, but it is extremely profound. DXM also combines incredibly with psychedelics. The best and strongest drug experience I've ever had was on LSD+DXM.

I could go on for hours about all of the incredible things DXM can do, but the unfortunate downside is that it's not for everyone - I would estimate that 1/4 people who try DXM will hate it - there's also a small subsection of the population that lacks the enzyme to break it down, meaning they will likely have an extremely long nightmare trip.

In conclusion, DXM is not just my favorite legal drug, it is my favorite drug.

And that's the end of this loooooooongpost. Hope you learned something. Or not. Idk.

If you have any questions about any of these drugs, feel free to ask - or you can always check out psychonautwiki.org and erowid.org for more information on psychoactive chems. We should definitely keep illegal sourcing out of this hole, but as all of these drugs are legal and OTC, feel free to ask for sources in this thread if you need a good brand.

Please comment with your own favorite and least favorite 'legal highs' (you know, if you want )

Hello everyone @Lapp here bringing you the second installment of

LAPPLAND'S CHEMICAL SERIES

I promised in the last installment that I would give details on how bathtub hrt is made but I couldn’t find enough info. Instead this will be all about cocaine. This is for @Chapose who wanted this specifically.

I @Lapp do not in any way endorse cocaine production or the consumption of cocaine nor does rdrama.net.

What is coca?

For thousands of years the native people of South America used the leaves of the coca plant for medicinal purposes and as a stimulant. Documents written by Spanish explorers show that consumption was a daily part of life for many indigenous people. Coca leaves would be consumed before hard labor, and it was also consumed at feasts and festivals and used as a religious offering as well. [1][2] Coca leaves were consumed by chewing or as tea. [3]

example of a coca plant:

What is cocaine?

Cocaine is a strong central nervous system stimulant. Cocaine was first isolated from the coca plant in its pure form, cocaine hydrochloride, by Friedrich Gaedck in 1855. [4] Purified cocaine was the main active ingredient in many tonics and elixirs developed to treat a wide variety of illnesses. Before anesthesia was developed cocaine was used by surgeons. [5]

Legal cocaine in the United States only started to decrease after the Jones-Miller act passed in 1922 started to put heavy restrictions on cocaine manufacturing. [6] Cocaine is considered a Schedule II narcotic making its possession illegal.

Use

Today cocaine is widely used as a recreational drug. Cocaine can induce feelings of euphoria, stimulate mood, and induce sociability. At high levels of consumption cocaine can cause paranoid actions, insomnia, anxiety, anger, overheating, and can lead to a heart attack.

Cocaine is still produced within the United States by medicine supply companies. It is still used by surgeons for numbing and to reduce bleeding in nasal and oral surgery.

Coca leaves are still consumed recreationally and are used as flavoring for soft drinks. To be used for soda they must undergo a process that removes the cocaine, which is how the previously mentioned medicine companies require it. The exact process used for this is not known but it can produce cocaine that consistently 95% pure or purer.

materials/chemicals

The following materials and chemicals are required for the production of cocaine:

1: dried coca leaves. The leaves picked from the coca plant must be dried for one to two days. If the leaf breaks under rubbing from a finger then it is considered to be fully dried. A dried leaf will lose ⅔ to ¾ of its weight during the process. [7]

2: lime or carbonate salt

3: kerosene (gasoline substitutable apparently)

4: dilute sulfuric acid

5: a metal drum or trough or pit lined with plastic capable of holding 55 gallons or over

6: water

7: potassium permanganate

8: ammonia

9: diethyl ether

10: hydrochloric acid

process

The first step of the process is to create what is known as coca paste.

To begin the dried coca leaves are broken down into small pieces and then dusted with lime or carbonate salt. After this they are dampened with a small amount of water. After this the solution is put into the metal drum or whatever holding device is being used. Next the kerosene is added to the coca leaf and the mixture is mixed for several hours. Though it can also be left standing and only occasionally mixed over three days. Once this process has run its course the solvent is removed by pressing, filtering or draining. The solvent extracted is then back-extracted with a smaller volume of dilute sulfuric acid which is added directly to the solvent, mixed vigorously for two up to ten, then allowed to sit and re-separate. The acid converts the cocaine free base to cocaine sulfate which is dissolved in the aqueous layer. The solvent is then separated, leaving only the dilute sulfuric acid solution of cocaine sulfate. This latter yellowish-brown solution is commonly referred to as agua rica or guarapo . The solvent can be reused indefinitely, with additions of fresh solvent to make up natural attrition due to handling and irrecoverable absorption into the leaf mixture. In the final phase of coca paste isolation, an excess of base, usually lime, carbonate, or caustic soda, is slowly added to the agua rica solution with stirring. The base neutralizes the sulfuric acid and converts cocaine sulfate back to the free base, which precipitates out of the solution as a gummy, yellowish solid.

The second step is to convert the coca paste into a coke base

The coca paste is first re-dissolved in a small amount of dilute sulfuric acid, recreating the aqua rica. The solution is then titrated against a concentrated aqueous solution of potassium permanganate which is a powerful oxidizing agent. Potassium permanganate gives an intensely purple solution when dissolved in water; as it reacts with the oxidizable alkaloidal impurities in coca paste, it is reduced to manganese dioxide, which precipitates out of solution. The over-addition or too rapid addition of potassium permanganate is known to result in decomposition and loss of cocaine, so the work must be done carefully to get it just right. When the permanganate is found to be complete, the solution is filtered to remove the precipitated manganese dioxide. The resulting colorless, slightly acidic solution still called agua rico is again treated with a solution of a base, commonly ammonia, with stirring. Again, the ammonia neutralizes the cocaine sulfate and any remaining sulfuric acid, thereby precipitating purified coke base. After this the coke base may have to be filtered again before the final step can be undertaken.

The final step is to convert the coke base into cocaine hydrochloride. It should be noted that any impurities in the final product not brought in by cutting are carried in by the coke base.

For this the coke base is dissolved into diethyl ether, filtered or decanted from any remaining insoluble impurities, and an equal volume of acetone containing a stoichiometric quantity of concentrated hydrochloric acid added to the filtrate with stirring. The hydrochloric acid immediately ion-pairs with the coke base to create cocaine hydrochloride, which begins to precipitate out of the solution as shiny white, flaky crystals. The use of excess concentrated hydrochloric acid shpuld be avoided because it caused the development of a distinct yellow color, which in turn can be partially conferred upon the cocaine hydrochloride. The resulting solution is allowed to sit from 3 to 6 hours in order to complete the crystallization process. Though it can also be heated with hot water from outside the container to reduce the reaction time to around thirty minutes. After completion of the crystallization process, the product should be filtered once more , dried under heat-lamps and/or microwave ovens. At this point the product is complete.

synthetic cocaine

It is also possible to produce synthetic cocaine the materials for which are as follows:

1: methylamine

2: succindialdehyde

3: acetonedicarboxylic acid

4: monomethyl ester

5: chloroform

6: dilute sulfuric acid

7: diethyl ether

8: pyridine

9: benzoyl chloride

10: dilute ammonium hydroxide

11:concentrated hydrochloric acid

The first step involves a ring coupling Mannich reaction using methylamine, succindialdehyde, and acetonedicarboxylic acid, and monomethyl ester in high dilution in a buffered, aqueous solution at 25°C. After 2 days, the reaction mixture is made basic and extracted with chloroform to give racemic 2-carbomethoxytropinone; tropinone is the major impurity.

In step two, the 2-carbomethoxytropinone is dissolved in a minimal volume of ice-cold dilute sulfuric acid and reduced to methyl ecgonine with a 1 to 1.5% Na/Hg amalgam at pH 3.5 and 5°C. The temperature and PH are critical, anything more or less than what is required will result in a bad batch. After several hours of sitting, the reaction is made basic, extracted with chloroform, and evaporated to an oil containing methyl ecgonine and pseudoecgonine methyl ester in an approximate 3/1 ratio. Additional impurities usually include tropinone, tropine, pseudotropine and unreacted 2-carbomethoxytropinone. The majority of pseudoecgonine methyl ester is precipitated from the oil by adding diethyl ether and then removed through filtration. The filtrate is evaporated to dryness, dissolved in diethyl ether and converted to hydrochloride.

In the final step, the methyl ecgonine hydrochloride is benzoylated with benzoyl chloride in pyridine near 0°C. After 24 h, the reaction mixture is allowed to warm to room temperature and is diluted with diethyl ether, which precipitates a cocaine HCl/pyridine HCl complex. This precipitate is filtered and washed with additional ether to remove any excess pyridine. It is then dissolved in water, and extracted with additional ether to remove benzoic acid. The resulting aqueous solution is made basic with dilute ammonium hydroxide (causing dissociation of the cocaine HCl/pyridine HCl complex), and repeatedly extracted with methylene chloride. The combined extracts, which also contain the remaining free pyridine, are evaporated to dryness to give cocaine base, which is re-dissolved in diethyl ether/acetone 1/1 and converted to the hydrochloride via addition of a stoichiometric amount of concentrated hydrochloric acid. [8][9]

Example of the Mannich reaction:

If you find yourself replicating any of these mentioned processes in part or in whole please contact your local law enforcement as cocaine is an illegal substance and should not be created or posessed in any way. A special thanks to @Modern_Major_General for proof reading this write up. If anyone else wants to help with that I could probably use one more person

Join me next time on Lappland’s chemical series where I teach you how LSD or MDMA is made I haven’t decided yet.

references

1: Mortimer, W. Golden. Peru History of Coca: "The Divine Plant" of the Incas. New York: J. H. Vail & Company, 1901.

2: Valdez, Lidio M., Juan Taboada, and J. Ernesto Valdez. 2015. "Ancient Use of Coca Leaves in the Peruvian Central Highlands." Journal of Anthropological Research 71 (2): 231–58. doi:10.3998/jar.0521004.0071.204 .

3. https://www.tni.org/en/publication/coca-leaf-myths-and-reality

4. Ueber das Erythroxylin, dargestellt aus den Blättern des in Südamerika cultivirten Strauches Erythroxylon Coca Lam

5. Calatayud J, González A. History of the development and evolution of local anesthesia since the coca leaf. Anesthesiology. 2003 Jun;98(6):1503-8. doi: 10.1097/00000542-200306000-00031. PMID: 12766665.

6. Cocaine : global histories

7. Casale JF, Meyers RP, Klein RFX: An in-depth study of cocaine base processing in the Chapare Valley, Bolivia;

8 https://erowid.org/archive/rhodium/chemistry/psychedelicchemistry/chapter8.html

9 https://www.erowid.org/archive/rhodium/chemistry/cocaine.illicit.production.html

In the interest of this hole not getting deleted again I thought I'd do little write-ups on some more obscure drugs every once in a while for anyone who cares. (* ^ ω ^)

Methqualone better known by its brand name Quaalude is a sedative drug that was introduced to the public as a sleep medication in the 1960s and popularized as a recreational drug in the 1970s. It would be discontinued in the US in 1985 and is presently a Schedule 1 drug. It's also banned pretty much everywhere else! Methqualone is probably best known to internet age users from videos like this.

The drug's effects are usually compared to benzos with some notable differences. Methqualone is heavily sedative but most users report a strong sense of simultaneous euphoria. Other primary effects include anxiety suppression and somewhat famously an increased libido. For many users however, the sleepiness induced by the drug overpowered all other effects.

It also kills the frick out of you if combined with any significant dosage of many other drugs. Alcohol being one of the primary culprits. Taking methqualone with booze, opioids, benzos, barbiturates, and more could cause you to slip into a coma and die without medical intervention. Due to the sedative effects, many people would combine it with stimulants to stay awake and to experience the euphoric effects for longer. Despite the risk from alcohol many users enjoyed 'luding out' which involved taking methqualone and wine at the same time.

A safe dosage of methqualone for first timers is reported to be around 100mg. The risk of overdose decreases as tolerances rises but the max dosage for heavy users (from what I can find) is about 8000mg. It's also very addictive! The most common withdrawal symptoms are an extreme insomnia and persistent feelings of anxiety. Other negative physical effects have also been reported like nausea, tremors, and even hallucinations (although some of those may just be occurring due to the lack of sleep).

If you wanted to get Quaaludes nowadays you're shit out of luck. They're not manufactured in any major country and you cant even get them by prescription. If you wanna make some methqualone yourselves there are various guides online, although from what I've read it's usually a pain in the butt and you don't get very much out of each batch.

Due to the difficulty in making homemade methqualone and the wall that most western countries have put up on its manufacture its usage has pretty much collapsed. And if you get your hands on 'some' it's probably just fent. Most of its usage has been historical as an aforementioned party drug. It was also notorious as a date r*pe drug. Some of you may be aware that Bill Cosby admitted to giving Quaaludes to some of his victims before raping them.

The drug remains popular in the developing world. In the 2000s methqualone was the most abused drug in South Africa, and in India it's still used illegally to this day. But for the rest of us, Quaaludes have been dumped into obscurity.

Here's what a package of quaalude looked like back in the day:

Further reading:

Erowid methqualone experience vault

Until next time crackheads

Frick I hate catnip users so fricking much, look at this and tell me this isn't terminal addict behavior.

President Joe Biden's Food and Drug Administration (FDA) is pushing to ban menthol cigarettes after it has pressed for safe crack pipe distribution and marijuana reform.

The FDA has pushed its long-awaited ban on menthol cigarettes, which some public health groups believe could help improve black communities and prevent young Americans from smoking cigarettes. Menthol cigarettes are viewed as more addictive than traditional cigarettes.

Tobacco companies have argued that there is no direct link between menthol cigarettes and starting smoking or even increased dependence on cigarettes. Black leaders, the American Civil Liberties Union (ACLU), and other similarly minded groups have voiced concerns that a menthol ban could lead to further policing of black communities.

While the Biden administration continues its nanny-state regulating of menthol-flavored cigarettes, it has made controversial moves to increase access to other drug paraphernalia and safe places to use illicit drugs.

In fiscal year 2022, the Department of Health and Human Services (HHS) began a $30 million grant program to provide funds to nonprofits and local governments to help make drug use safer for addicts. A spokesman for the agency told the Washington Free Beacon that grants would provide pipes for users to smoke crack cocaine, crystal methamphetamine, and "any illicit substance."

A $5 million grant to New York University and Brown University funded an investigation into if overdoses can be prevented by "safe injection sites" --- or places where drug addicts can use heroin and other illegal drugs and can be revived if they use too much.

Biden has also moved to pardon those convicted of marijuana possession under federal law, urged governors to do the same, and moved to review how marijuana is scheduled under federal law.

Jeffrey Singer, a senior fellow at the libertarian-leaning CATO Institute, wrote Tuesday that the menthol tobacco ban would lead to a stronger black market in cigarettes:

In my comments, I stated that, according to the National Survey on Drug Use and Health, in 2020, 81 percent of Black and 51 percent of Latinx smokers preferred menthol-flavored cigarettes. While the proposed rule is intended to reduce tobacco-related health outcome disparities in Black and Brown communities, a closer look at the data on menthol cigarettes, as well as the European Union's experience with a menthol ban, suggest that the proposed product standard will not work, and will likely foster a black market. Perhaps even worse, the ban might further aggravate criminal justice inequities.

Citing various studies, Singer argued:

• Menthol cigarettes "are no more, and perhaps less, harmful than non-menthol cigarettes."

• Menthol cigarette smokers have a lower cancer mortality risk than non-menthol cigarette smokers.

• Despite the ban focusing on lowering teenage use of cigarettes, 60 percent of teen smokers smoke non-menthol cigarettes.

"Sadly, it appears the menthol‐ban train has already left the station. This means more business opportunities for purveyors of black market products---ranging from illicit drugs to cigars and cigarettes," he added.

"And if history teaches us anything, we can expect to witness many harmful unintended consequences," Singer concluded.

I spent $75 dollars on this. Many unsuspecting individuals have seen me on the stairs of my apartment complex taking massive rips off this pile of shit every night or so. Should I keep myself safe?

Around a year ago I started engaging in a lot more drug related degeneracy. I'm young, in college, and figured that it was something I wanted to try. I had also been drinking consistently for some time before that and gotten bored of alcohol, so finding something new was appealing. I basically progressed through a bunch of different substances, gradually getting bored of each one.

It started with weed. After around a week of usage I got less and less interested because it made me much less productive and I felt like a cute twink. 99% of the people I know who smoke weed on a regular basis are low functioning r-slurs. Plus, I wanted something more intense. This was when I found LSD, which is probably the drug that has held my interest the longest. At one point last year I was taking two tabs roughly every 1-2 weeks for a couple months. Tried microdosing, sitting in the dark alone, partying, overall great drug. Honestly I feel like I discovered this substance too early, since taking LSD also killed any desire I had to smoke, drink, or take mushrooms like I used to.

Shrooms were basically lower energy acid. Still felt like a bit of a cute twink for using them. The vibes are off, I wanted something more social. That was when I found MDMA, which also held my interest for some time. Started taking it for parties I would go to with friends and it was an excellent time. Fricking while on Molly is also close to life changing. But the next day depression streaks were tiring so I gradually have just stopped using it. I also tried DMT, but I felt like a loser since I had to smoke it with this fricking r-slurred hippie guy. Overall it was cool but not something I'd prefer to repeat. Coke has been my most recent experiment, and I had fun with it for about a week before I lost interest. I also tried opiates once, (unintentionally) meth, and 2CB. All felt relatively mid.

This brings me to today. I currently have access to basically every drug I listed, clean, and for dirt cheap or free. I even have some of each left over. But I literally just have no interest in taking them. Not in a party setting, not chilling with friends, and definitely not alone. I feel like I've gone through all of them, gotten a variety of experiences, and there's nothing really left for me. To be completely honest, LSD absolutely obliterates any other drug I've tried and anytime I try something new I end up comparing it to that, which obviously, it can't. Now, aside from social drinking at parties and an occasional drunk cig I am basically sober. Not because I had a grand revelation about drugs being bad for me, or that I don't have the time for them anymore, or even the negative side affects. I just don't want to anymore. It's boring. Is this relatable to anyone else or am I r-slurred?

And before some r-slur comes in here and says "haha no bro it's because you haven't tried the real shit! meth, heroin, fentanyl, and [inset drug] are where it's at!" First of all, you're simply wrong. I didn't include opiates in this list but I've tried them and they're shit. You realize you're doing poor people drugs right? Meth is for people who can't afford MDMA and opiates are for fat midwesterners. I am convinced that there is not a single drug on this planet that is more "intense" or "better" than some combination of LSD/MDMA, and even if there was, I would probably get bored of it anyway. I literally cannot fathom ruining your life/body/mind for an experience as mediocre as mild opiate euphoria. If you're smart, drugs should always be a cost/benefit analysis, and the idea of shooting up heroin for an experience objectively worse than a $2.50 tab of acid is r-slurred.

So it turns out that everyone already knew what quaaludes were but me because of Wolf of Wall Street o(> < )o so this time I picked one with a whole bunch of analogues so I can say that it's technically obscure cause maybe you just did 25C-NBOMe instead.

25I-NBOMe is a hallucinogen first synthesized in 2003 by some German guy at a university in Berlin as a part of his PhD dissertation. Since then there has been a legion of analogues all in the same family that were created during the 2000s and have been increasing in popularity since.

The drug has various street names, most commonly "N-bomb" which is kind of funny. Unfortunately however most people just call it LSD when they sell it to you (it's not LSD).

It's passed off as LSD because the effects are comparable and it's easy to because both commonly come on blotters and are best taken in micrograms (μg) under the tongue. While there are distinctions between the two effect-wise it can be difficult to discern because pretty much all reporting on this drug comes from individual experiences. It can be hard to pull real truth of out of subjective anecdotes. Especially from dudes that are tripping. Also side note: never snort Nbome.

One thing that you can find in a host of trip reports is that Nbome is much less introspective than LSD. There's no ego death or 'maybe I have childhood trauma' realizations while tripping on Nbome (although some people still report these happening). Also, the visuals are much stronger than LSD. Many people report a kind of 'disco ball' effect or a fragmentation of light in the visuals. For some people this is cool, for others it's deeply uncomfortable and in the worst cases it's terrifying. Visual 'fish-eyeing' has also been reported where objects seems closer depending on how you're looking at them. Another thing that can be pulled out of Nbome reports is that it has a tendency to go real bad real fast. Bad trips seem more common, this might be a result of the physical effects that come with the drug.

Luckily for us Nbome has a host of physical effects that LSD doesn't that make it a little easier to differentiate the two. Unluckily, these physical effects are all harmful. Nbome has been found to be neurotoxic and cardiotoxic. Numerous confirmed overdoes have been recorded since the drug's introduction into society. It can cause seizures, hyperthermia, hypertension, vasconstriction, kidney damage, and more! Basically any effect that you would get from toxidrome syndrome you can get by taking too much Nbome. Most of these problems only arise with higher doses, doses that would otherwise probably be safe if you were taking LSD, which you might have thought you were doing when you took it.

With respect to dosing a beginner dose is around 200 μg. Maximum recommended dose seems to hover at around 1500 μg but the risk of adverse effects and overdose will rise with an increased dose (obviously) so it's best to start small and work your way up.

That all being said, Nbome also comes with the usual of LSD, euphoria, pupil enlargement, vibes, ect. And on top of the added overdose concerns all of the usual precautions about psychedelics apply.

Despite the dangers some people swear by Nbome. Claiming that it's a better high than LSD or shrooms. Regardless of what you think, if you get your hands on this stuff don't be a moron with it. I assume overdosing while you're tripping is one of the more horrible ways to die.

Deaths related to Nbome were a godsend for mass media and your uncle who's a pastor on facebook because it allowed them to report these deaths as being caused by LSD. Now LSD does have some toxicity, but it's not even close to Nbome's toxicity. As far as I know there are no confirmed deaths from LSD alone, although it has been a complicating factor in a few. But that didn't stop anyone from misreporting the deaths as being caused solely by LSD. While most of the media has come around and knows the distinction nowadays, your uncle on facebook probably still doesn't.

So what if you just wanna drop some fricking acid like a normal person and you don't want your kidneys to fail? Well there are test kits around that test for Nbome, if you're planning on tripping sometime soon I'd recommend getting one. If you don't wanna then the final line of defense is a taste test. Nbome is incredibly bitter compared to LSD, I don't know how well this would actually work but I figure you could put a corner of a tab in your mouth and spit if it's bitter.

The drug isn't hard to synthesize and you can find out how to do it online if you really wanna. It's apparently pretty easy to make which is likely why it's become such a problem since it was first synthesized. If you do take it then take a moderate dose and have someone sober to watch you and if you have a bad trip don't sell the rest of it to some poor kid who doesn't know better.

Here's what a blotter of 25C-Nbome looks like (not LSD btw) I assume that 25I looks pretty much the same:

Further reading:

Article about it from 2013

Ye old Erowid vault

A particular bad trip that made me sad

>I asked my friends to just hold my hand. That's all I wanted. I thought that in a world of death and chaos, that requesting light affection and then receiving it would confirm that I'm still alive, that what is happening to me is only temporary and not reality, so I cannot express the feelings of hurt when my friends wouldn't even hold my hand.

Until next time tweakers

I should try coke for the holidays.