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A company manufactured drugs for AIDs in space

https://gizmodo.com/california-startup-varda-space-drugs-capsule-return-1851298876

The company is Varda Space. They are experimenting with manufacturing drugs in space. Their first batch returned to earth today, landing in the Utah desert.

I know you're asking: why manufacture drugs in space? Well basically when creating crystals on earth, there is sometimes a more stable but less useful form that ends up emerging. I don't really understand this ( I failed chemistry lol) but kinda interesting

https://en.wikipedia.org/wiki/Disappearing_polymorphs

The specific drug made in space is called Retonavir, which is used for helping with HIV patients. So no, the title of this post wasn't even a joke. Lest you think that I made this up:

https://www.healio.com/news/infectious-disease/20240222/hiv-drugs-manufactured-in-space-return-to-earth

Outside of the memes, this is pretty neat. Who knows what other stuff we will manufacture in orbit, with the cost of space launches decreasing?

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The mission, though stranded for months, turned out to be historically significant, achieving two new and important milestones.

Darn that's insane! I wonder what kind of disaster could cause the payload to become stranded?

The mission was originally supposed to return in September 2023 but was denied reentry to Earth by the Federal Aviation Administration (FAA).

:#marseyunamused:

the FAA was the real disaster all along

https://i.rdrama.net/images/17093966764992774.webp

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I would only support pic related if the ship was full of AIDS experiments

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Raman Spectroscopy is used a lot to inspect product for quality control and to monitor batches for potential polymorphs which reduce solubility and dissolution of doses, this could potentially alter the pharmokinetics of stuff or make it less effective or even beget harmfull side effects from dosages. !chuds

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I like that you tagged chuds on this. !nonchuds simply aren't intelligent enough to understand science

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:marseyprojection:

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Nonchud janny must have made your Marsey gold

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!slots100

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!slots100

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Girls can be born with a peepee!

Weird right?

I fricking love science!

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Are you saying that the polymorphs are good which means that eliminating them is bad?

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No, it's a quality control issue. Selling drugs that may have batches with altered chemistry opens up to liability if anyone sues for being rendered infertile or whatever.

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So it's an issue where since it's effectively a new drug, you have a new set of potential side effects?

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Yes. Also issues of copyright and patents. Chemical formula and processes are trade secrets and viciously defended. Polymorphs can ruin product via contamination. If your manufacturing is contaminated it can only then produce that polymorph and not the original drug. GSK has an INSANE case about this where generic drug companies were actually making a GSK polymorph.

In his comprehensive monograph on crystallization, Mullin notes that, “Atmospheric dust frequently contains particles of the crystalline product itself, especially in industrial plants or in laboratories where quantities of the material have been handled……Once a certain crystalline form has been prepared in a laboratory or plant, the working atmosphere inevitably becomes contaminated with seeds of the particular material.”

"When the patent for paroxetine anhydrate (the "original" polymorph) ran out, other companies wanted to make generic antidepressants using the chemical. The only problem was that by the time other companies began manufacturing, Earth's atmosphere was already seeded with microscopic quantities of paroxetine hemihydrate from GSK's manufacturing plants, which meant that anyone trying to manufacture the original polymorph would find it transformed into the still-patented version, which GSK refused to give manufacturing rights for. As it is illegal to manufacture or sell anyone's patented product without their permission, GSK sued the Canadian generic pharmaceutical company Apotex for patent infringement by producing quantities of the newer paroxetine polymorph in their generic pills, asking for their products to be blocked from entering the market. GSK eventually lost the case on a technicality in the U.S. Federal Circuit Court."

!nooticers

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479028/#b23

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That is pretty insane actually, wow

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Sounds bogus

In his comprehensive monograph on crystallization, Mullin notes that, “Atmospheric dust frequently contains particles of the crystalline product itself, especially in industrial plants or in laboratories where quantities of the material have been handled……Once a certain crystalline form has been prepared in a laboratory or plant, the working atmosphere inevitably becomes contaminated with seeds of the particular material.”

We manufacture pharmaceuticals and sensitive electronics in clean rooms for this very purpose

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Kinda r-slurred. If you contaminate the entire world with your crap, you should at least be taken out back and shot.

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:taymindblown:

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They talk about Raman spec for like 5 seconds in analytical chemistry and then go back to IR

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:marseyantiwork: my old tutor focused on it for a good bit but I think that was because his own research was using it a lot.

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One of our inorganic chem. pofessors went over it with us as it's more of a material science thing anyways

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Inorganic and physical chemists are subhumans. I'd rather kms than deal with a schlenck line again.

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Fun fact for our local sexy Indian dudes :marseytunaktunak: Raman is named after a :marseypajeet:

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I'm imagining some SEGA Dreamcast Y2K styled multiplayer game where you have to perform heists on the space drug labs so you can continue to bussy blast without using a condom :marseyembrace:

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Space AIDS drugs will finally enable fully automated gay luxury space communism

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https://i.rdrama.net/images/17094168817075686.webp

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I'm starting a fundraiser to add a catboy module to the ISS

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Globetards and getting AIDS, name a more iconic duo

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>the Utah Desert

that's the whole state

the title should have said the UTTR, but the body doesn't indicate North or South Area of I-80

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Oh good, all those hundreds of billions spent on the ISS and now they're using it to make gucci AIDS drugs for gay billionaires.

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