RETARDED @SERGE am going too try being on estrogen for a while 29/12

Couple of Issues with your comment:

Spironolactone was indeed first introduced as a Mineralocorticoid (Aldosterone) Receptor Antagonists, but has been studied and classified as an antihormone for literal decades. As we know, medication can be created for a purpose but later be found to also have additional effects. You will find the viagra that you will be needing in a few months has such a history also. Spirolactone is a testosterone antagonist, therefore it can be categorized as an anti-androgen. That is not controversial, try searching around pubmed for a bit. Your assumption it is only used as such in North America is misinformed, are you one of these euros that assume that only the US and (western) Europe exist? It is used not only for train medicine but in treatment of female conditions of elevated androgen levels such as hirsutism.

Your definition of "superior" androgen suppression is not exactly founded in medical consensus. cyproterone acetate is indeed a valid alternative, but it is not without serious side effects (hope you don't develop that brain tumour, bb!) or provably "better" than spironolactone. Studies are only coming out very recently.

No eligible studies adequately evaluated the effects of antiandrogens on breast development or facial and body hair reduction. It remains unclear which antiandrogen is most effective at achieving feminization. Cyproterone acetate, medroxyprogesterone acetate and leuprolide may be more effective than spironolactone at suppressing the serum total testosterone concentration. However, due to spironolactone's antagonism of the androgen receptor, it is unclear whether this results in clinically meaningful differences in feminization. Further research with clinically meaningful endpoints is needed to optimize the use of antiandrogens in transgender women.

You affirm "you dont need an antiandrogen if you're estrogen dosage is high enough." but that is merely conjecture (in fact more likely anti-androgens by themselves are more effective in feminizing than estrogen by itself. Testosterone is quite a drug after all). Have you perhaps already castrated yourself? Otherwise

[O]estradiol alone is usually insufficient to lower serum total testosterone concentrations from a male to a female reference range. Oestradiol suppresses gonadotropin-releasing hormone (GnRH) via negative feedback, in turn partially lowering testosterone. However, as the majority of individuals (82% in our clinics (1)) do not undergo genital reassignment surgery to remove the testes, which are responsible for >95% of testosterone production, most individuals will require treatment with an additional anti-androgen drug.

Watch yourselves chuds, she's done her homework. This is what advanced biology looks like

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