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Are there any drugs that cause fast acting depression and sadness? (like the opposite of MDMA)

I've been wondering this for a while

17
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I don't know how fast acting it is, but the pharmacologists once came out with rimonabant, a cannabinoid receptor inverse agonist. Coarsely speaking, the opposite of weed. The theory was that weed makes you hungry, this anti-weed would make you lose your appetite and control obesity. Trials were unsuccessful since it also turned out as weed lifts your mood, rimonabant makes you suicidal.

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:#marseyspitmoji:

https://i.rdrama.net/images/17224783190832577.webp

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>Invent anti-weed

>Cartoon logic turns out to be true

lmao what the frick

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when u give them a 2.8 of the evil weed instead of the 3.5 of normal bud

:#marseytroll:

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