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Are there any drugs that cause fast acting depression and sadness? (like the opposite of MDMA)

I've been wondering this for a while

17
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I don't know how fast acting it is, but the pharmacologists once came out with rimonabant, a cannabinoid receptor inverse agonist. Coarsely speaking, the opposite of weed. The theory was that weed makes you hungry, this anti-weed would make you lose your appetite and control obesity. Trials were unsuccessful since it also turned out as weed lifts your mood, rimonabant makes you suicidal.

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:#marseyspitmoji:

https://i.rdrama.net/images/17224783190832577.webp

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>Invent anti-weed

>Cartoon logic turns out to be true

lmao what the frick

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when u give them a 2.8 of the evil weed instead of the 3.5 of normal bud

:#marseytroll:

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Probably something that guarantees a bad trip like Benadryl

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yea but i think dosage matters to get exactly what he wants. and it also comes with brain damage so he prolly not goin for this one

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The sparkle gremlins were ultimately harmless.

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...how many of you !boozers would argue this case?

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Does MDMA make you cold and lame? If not then booze is not opposite

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i drink because i am depressed and i am depressed because i drink

:#marseygiveup:

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like fat bastard, viscious cycle

https://media.tenor.com/h0xTj5WjgcUAAAAx/fat-bastard-gold-member.webp

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alcohol is a depressant. dont know if it counts as fast acting though.

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Just take too much MDMA repeatedly and you'll probably get what you want.

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Swanson's hungry man dinners (expired) I hope.

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Mdma and cocaine, I don't know if you consider "the day after" to be fast acting or not

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alcohol

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:#marseyblm:

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suppose the right dose of alcohol or a deliriant. maybe a little under a threshood dose of the deliriant

even though i feel great on opiates ppl often tell me i look sad n shit like "cheer up". but thats just how i look not how i feel

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Just the right amount of alcohol

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huff paint, or do jenkem

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