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Are there any drugs that cause fast acting depression and sadness? (like the opposite of MDMA)

I've been wondering this for a while

17
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...how many of you !boozers would argue this case?

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Does MDMA make you cold and lame? If not then booze is not opposite

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i drink because i am depressed and i am depressed because i drink

:#marseygiveup:

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like fat bastard, viscious cycle

https://media.tenor.com/h0xTj5WjgcUAAAAx/fat-bastard-gold-member.webp

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alcohol is a depressant. dont know if it counts as fast acting though.

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