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Little evidence that chemical imbalance causes depression, UCL scientists find

https://www.theguardian.com/society/2022/jul/20/scientists-question-widespread-use-of-antidepressants-after-survey-on-serotonin

Scientists have called into question the widespread use of antidepressants after a major review found “no clear evidence” that low serotonin levels are responsible for depression.

Prescriptions for antidepressants have risen dramatically since the 1990s, with one in six adults and 2% of teenagers in England now being prescribed them. Millions more people around the world regularly use antidepressants.

“Many people take antidepressants because they have been led to believe their depression has a biochemical cause, but this new research suggests this belief is not grounded in evidence,” said the study's lead author, Joanna Moncrieff, a professor of psychiatry at University College London and consultant psychiatrist at North East London NHS foundation trust.

“It is always difficult to prove a negative, but I think we can safely say that after a vast amount of research conducted over several decades, there is no convincing evidence that depression is caused by serotonin abnormalities, particularly by lower levels or reduced activity of serotonin.

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they've known this for years and is universally accepted by doctors

nobody really knows jack shit about the brain, or why it does what it does (depression, anxiety, mental illness) or even why medications work

:#marseyshrug:

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Add in TBIs to that list, nobody has a clue if someone will recover 10/50/100% of their pre injury capabilities

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Yeah any person who has done a modicum of research on the pills they take will find no one knows how the frick pills work.

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