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MayoAntiRacist I/me  1yr ago (en.wikipedia.org) 376 thread views #198281

HeLa cells have 76-80 chromosomes. Upmarsey if you agree that that's TOO MANY!

https://en.wikipedia.org/wiki/HeLa#Chromosome_number
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HeLa cells are sometimes difficult to control because of their adaptation to growth in tissue culture plates and ability to invade and outcompete other cell lines. Through improper maintenance, they have been known to contaminate other cell cultures in the same laboratory, interfering with biological research and forcing researchers to declare many results invalid.

:marseyworried:

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You'd have to be pretty r-slurred to mix cell lines like this. This has never been a problem for me.

https://i.rdrama.net/images/17187151446911044.webp https://i.rdrama.net/images/17093267613293715.webp https://i.rdrama.net/images/17177781034384797.webp

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I can imagine some RA or grad student getting lazy while splitting cells and using the same pipette/tip for draining the media or doing washes.

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Then you get exactly what you deserve.

https://i.rdrama.net/images/17187151446911044.webp https://i.rdrama.net/images/17093267613293715.webp https://i.rdrama.net/images/17177781034384797.webp

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It's why I don't let anyone else touch my cells. Trust no one.

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HeLa cells are literally cancer cells. The whole reason they are used is because they multiply like crazy.

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And refresh their telomerase constantly. The cells are literally immortal, unless they get irradiated or heated up too much

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my mamaw said that before the deluge, humans had stronger telomeres (or smth like that) and possibly more chromosomes

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Methuselah had the ideal number of chromosomes: 69

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I'm a bit confused about why they're still used. They're basically not even human cells at this point, right?

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Different cell lines for different things. If you're looking for how well your drug can kill fast replicating cells (how most traditional chemotherapeutics work) then they can be good. Most cell lines used for research are immortalized because having to get new cells shipped for every experiment is expensive. Still have to do it for some types of cells like for immunology research though.

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