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Pibbles it/its I eat children :marseythumbsup:  2yr ago (reddit.com) 2,556 thread views #87688

:marseychemist::marseydoomer:Study confirms the "chemical imbalance" is a meme and seratonin has nothing to do with depression. An entire generation of brain addled SSRI zombies copes

https://old.reddit.com/r/science/comments/w4ioxk/the_serotonin_hypothesis_debunked_in_a_recent 

								

								

									
									
Scientology is right about psychiatrists.


									
								

							

							

								
									
								
							

							

								
	

							

						

						
						

							

								
							

						

					

					
						

							
							
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I'm not about to explain a multiaxial etiology on my phone, but cope. Definitely a meme that something proven to upregulate 5ht1a postsynaptic receptors might improve SSRI side effects

						


						
							

							

								
									
								
							


							

								
	

							


							

								

									

										
										

									


								
						

					
				


				

				
					
	

	
		

			
		


		

			

				
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:#marseytinfoil2:

						


						
							

							

								
									
								
							


							

								
	

							


							

								

									

										
										

									


								
						

					
				


				

				
					
	

	
		

			
		


		

			

				
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Can you tell me what a 5ht1a postsynaptic receptor does? I don't care if anybody believe it, I'm just tryna help point other people suffering like I used to in the direction of what helped, and there's very solid neuroscience behind it :marseyshrug:

						


						
							

							

								
									
								
							


							

								
	

							


							

								

									

										
										

									


								
						

					
				


				

				
					
	

	
		

			
		


		

			

				
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Then why not just link to a single peer-reviewed study that even remotely supports your schizopothesis.

						


						
							

							

								
									
								
							


							

								
	

							


							

								

									

										
										

									


								
						

					
				


				

				
					
	

	
		

			
		


		

			

				
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here I can link you to hundreds! https://scholar.google.com/scholar?hl=en&as_sdt=0%2C1&q=st+john%27s+wort+5ht1a+upregulation&btnG=
https://www.sciencedirect.com/science/article/pii/S0166432808007171?casa_token=NjjqvkM14zMAAAAA:apDyW4uVX5JWeIWQU1-zIY804xvnpScyyvOUVe70NQsHDM-c9tZBVWVA-e767AYJuQGlXofF
https://www.nature.com/articles/4000557.pdf?origin=ppub
https://journals.sagepub.com/doi/pdf/10.1177/026988110101500109?casa_token=uSmksWjPfzoAAAAA%3AVT_hIYEXqdfZhwKSOrr6E1r1mSx-kPO35dpJyNmx8MhNFLBewMq2lhXlP_HGAn49_8YZifkiwHY&
Here's one about the specific cultivar I recommended! https://pubmed.ncbi.nlm.nih.gov/11518078/
And testimonies from thousands of other people https://www.google.com/search?q=st+john%27s+wort+pssd&oq=st+john%27s+wort+pssd
Isn't it neat that you can find that stuff in like 5 seconds? What a time to be alive! It's been extensively studied for decades and used for this exact purpose by tens of thousands of men. Now quit being a lazy brainlet and don't make me do this emotional labor for you again.

						


						
							

							

								
									
								
							


							

								
	

							


							

								

									

										
										

									


								
						

					
				


				

				
					
	

	
		

			
		


		

			

				
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Based educatedcel

						


						
							

							

								
									
								
							


							

								
	

							


							

								

									

										
										

									


								
						

					
				


				

				
					
	

	
		

			
		


		

			

				
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I mean I get the reaction, 99.99999% of herbal "medicine" is snake oil and I was extremely skeptical too. I didn't even really believe it either for weeks after it started to actually work :marseyshrug:
Which is specifically why I recommend this brand that costs ten times what you could grab at CVS, because those are just whatever the frick happened to be growing whilst this is studied produced and regulated as an actual medicine

						


						
							

							

								
									
								
							


							

								
	

							


							

								

									

										
										

									


								
						

					
				


				

				
					
	

	
		

			
		


		

			

				
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I always read research or ask doctors in my circle before buying random supps. I can usually understand papers but at some point I get annoyed looking up all the random shit I need to know to comprehend papers on topics I have little knowledge of.

						


						
							

							

								
									
								
							


							

								
	

							


							

								

									

										
										

									


								
						

					
				


				

				
					
	

	
		

			
		


		

			

				
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And that's exactly what you should do. I think I spent at least 300 hours researching shit on my own over a few months before making my way down the list of potential remedies to this one. And it was the one that actually worked. I have no idea if the probiotics actually made a difference but there's enough of a logical pathway (95% of serotonin is in your gut, and bacteria steal bloodflow from your pelvis, and good bacteria can scavenge ammonium) to recommend it since it's cheap and harmless
I don't tell my psych tho, he thinks I still need the adderall :marseytroublemaker:

						


						
							

							

								
									
								
							


							

								
	

							


							

								

									

										
										

									


								
						

					
				


				

				
					
	

	
		

			
		


		

			

				
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Thanks for doing all the work for me nerd. I was kinda interested.

						


						
							

							

								
									
								
							


							

								
	

							


							

								

									

										
										

									


								
						

					
				


				

				
					
	

	
		

			
		


		

			

				
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7 =/= 100

						


						
							

							

								
									
								
							


							

								
	

							


							

								

									

										
										

									


								
						

					
				


				

				
					
	

	
		

			
		


		

			

				
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The first link has 420 papers (dude weed lmao)

						


						
							

							

								
									
								
							


							

								
	

							


							

								

									

										
										

									


								
						

					
				


				

				
					
	

	
		

			
		


		

			

				
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:marseyxd:

						


						
							

							

								
									
								
							


							

								
	

							


							

								

									

										
										

									


								
						

					
				


				

				
					
	

	
		

			
		


		

			

				
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:#marseytinfoil:

						


						
							

							

								
									
								
							


							

								
	

							


							

								

									

										
										

									


								
						

					
				


				

				
					
	

	
		

			
		


		

			

				
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